NOW 5-HTP 200MG 60Caps
5-HTP is an intermediate metabolite between the amino acid L-tryptophan and serotonin that helps to support healthy mood balance and reduce symptoms of fibromyalgia. There has been recent interest in the use of 5-HTP as a means to boost serotonin production. 5-HTP is a precursor to serotonin. This is the most synergistic and complete 5-HTP supplement offered by NOW. This vegetarian formulation is extracted from the seed of the African Griffonia simplicifolia plant.
Serotonin (5-HT) is a neurotransmitter synthesized centrally from derivatives of the essential amino acid, tryptophan. 5-hydroxytryptophan (5-HTP) is created in the body via tryptophan hydroxylase, which is subsequently decarboxylated to serotonin (5-HT). 5-HTP is readily absorbed when taken orally and crosses the blood-brain barrier to increase the central nervous system (CNS) synthesis of serotonin. Serotonin can affect sleep, appetite, temperature, sexual behaviour, and pain sensation. Serotonin also has a significant role in depression, anxiety, and aggression. 5-HTP is one of the few approved natural therapies for fibromyalgia with the possibility of reducing pain severity, morning stiffness, and sleeplessness. 5-HTP has been shown to increase neurotransmitting catecholamines such as dopamine and norepinephrine that are synthesized from tyrosine. There is speculation that increasing the availability of tyrosine to the brain allows increased neurotransmitter synthesis which helps to counter the negative effects of stress. The addition of B-vitamins to this formula provides additional synergistic effects as they enhance the metabolism of amino acids.
Adult Dosage: To minimize the risk of gastrointestinal side effects, slowly increase dose to effective levels over a period of 2 weeks. For use beyond 1 year consult a health care practitioner.
Fibromyalgia: Take 1 capsule 2 times daily with food. Use for a minimum of 2 weeks to see beneficial effects.
Mood balance: Take 1 capsule 1-3 times daily with food. Use for a minimum of 1 week to see beneficial effects.